Variation in transplacental transfer of tyrosine kinase inhibitors in the human perfused cotyledon model
نویسندگان
چکیده
منابع مشابه
Variation in transplacental transfer of tyrosine kinase inhibitors in the human perfused cotyledon model.
BACKGROUND The use of tyrosine kinase inhibitors (TKis) during pregnancy in humans remains rare, and little data are available on their transplacental passage. Erlotinib and gefitinib are the first-line targeted therapy in case of stage IV nonsmall-cell lung cancer with an EGFR-activating mutation. There are no data available regarding the comparative use of these TKis in pregnant patients. We ...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2015
ISSN: 0923-7534
DOI: 10.1093/annonc/mdv172